CATEGORY
Serum
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Category Alerts
Thermo Fisher Expands Animal Origin Free Media Manufacturing Capacity
August 08, 2022Pristine Biologicals Expands Production Capacity
July 14, 2022Successful Transition of Cell Line Development With Animal Origin Component Free Media
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Serum Market Monitoring Dashboard
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Serum Industry Benchmarks
Savings Achieved
(in %)
The average annual savings achieved in Serum category is 20.10%
Payment Terms
(in days)
The industry average payment terms in Serum category for the current quarter is 54.3 days
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Category Strategy and Flexibility
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Sourcing Process
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Contract Length
SLAs/KPIs
Lead Time
Supplier Diversity
Targeted Savings
Risk Mitigation
Financial Risk
Sanctions
AMEs
Geopolitical Risk
Cost Optimization
Price per Unit Competitiveness
Specification Leanness
Minimum Order Quality
Payment Terms
Inventory Control
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Serum Market Intelligence
global market outlook
- The global market size is 660,000 Liters in 2021 and the market is expected to grow at a CAGR of approx. 8–9 percent to 1077,000 liters by 2027
- The APAC region is leading in the supply of FBS, limited demand exists for FBS in the Asian region. Several organizations in North America have been involved in the development of COVID-19 vaccines and drugs, which has increased the demand for FBS
- Australia and New Zealand-origin serum or FBS are considered to be superior to other regions of origin. This is because of the low BSE or disease risk that these regions hold. However, the serum activity is found to be similar across all serums and other alternatives, like US-origin serum, can be considered.
- The US-origin serum is also gaining more popularity ever since its upgrade to the negligible BSE risk category by OIE. Brazil or South American origin serum is considered as a low-cost alternative for the US-origin serum. Currently, it is more prevalent in the R&D segment than in manufacturing
- Fetal bovine blood is the basic raw material used in the manufacture of Fetal Bovine Serum. The price of fetal bovine blood varies significantly due to various factors, such as herd rebuilding, drought, etc. This is the major cost component in the manufacturing of Fetal Bovine Serum

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Serum market frequently asked questions
The worldwide serum supply in 2020 was around 704,000 L. As per Beroe’s category intelligence report, the global serum market will grow at 4-5% CAGR over the next five years, reaching nearly 899,000 L total volume.
Rapid growth in the biopharmaceutical industry has been the primary driver for the global serum market. The fetal bovine serum (FBS) has been supplementing cell culture media for several decades. Furthermore, increasing demand from emerging regions, such as South Korea and other developing nations, will likely offer another leg of growth.
While the US holds a significant revenue share in the global serum market, players prefer Australia and New Zealand for sourcing FBS owing to the lowest risk of transmissible spongiform encephalopathy (TSE) and bovine spongiform encephalopathy (BSE).
Specific ethical, scientific, and supply challenges have compelled researchers to look for a substitute for FBS. Moreover, the supply of FBS is limited and is subject to various factors including, cattle cycles, beef demand, and weather patterns. Furthermore, issues with the supply chain monitoring of FBS are impacting manufacturers’ bottom lines.
While there is a shift towards artificial serum, animal-based serums, especially FBS, find use in specific applications. Further, think tanks have dedicated several years to research in order to discover a substitute to FBS; however, they have yet to find a solid alternative.
The US, Brazil, and Australia are the major serum producers worldwide. While the North American serum market is growing at a 4-5% CAGR, the market size in Europe is expanding at around 5% CAGR.
Serum market report transcript
Global Market Outlook on Serum
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Supply market for FBS is split across the US, Australia, Brazil, etc. The US contributes to the highest market share, which is greater than Australia and New Zealand
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Dual sourcing of FBS is usually followed by major pharmaceutical companies for commercial manufacturing and R&D applications
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Suppliers are evaluated for long-term supply assurance and traceability of serum
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Usage of South American origin FBS has increased, particularly in the research community
Impact of COVID-19 on FBS
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FBS supply and pricing are dependent on several factors, such as environmental, geopolitical, etc. Hence, the supply continuity and price stability may be inconsistent to an extent
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Scientists have spent several years in research, trying to find an alternative to FBS, but there is no solid alternative till date
Serum Market Overview
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Volume of FBS produced globally in 2020 is estimated to be around 704,000 L. The US, Australia, and Brazil are some of the major regions for FBS production.
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The global FBS market is projected to grow at a rate of 4–5percent for the next five years and reach a total volume of nearly 899,000 L by 2025
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New Zealand and Australia, having the lowest risk of BSE and TSE, are the most preferred locations for sourcing FBS
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Increasing demand for FBS, coupled with slow growth in raw material fetal bovine blood (FBB), is one of the key challenges in the market
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Although there is a shift toward artificial serum, there are certain applications for animal-based serum (especially, FBS), which cannot be overseen
Industry Drivers and Constraints
Drivers
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Demand for FBS has been driven by the rapid growth in the biopharmaceutical industry. Cell culture media has been supplemented by FBS for many decades now
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Demand from new regions, like South Korea and other developing countries, is expected to fuel the demand for FBS
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FBS sourced from New Zealand and Australia are always preferred over any other serum, since they are free from any risk and assumed to offer better results
Constrains
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Due to the certain scientific, ethical and supply challenges, researchers have been forced to identify an alternative for FBS
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Supply of FBB is finite and it often affected by factors, like weather pattern, dairy market, cattle cycles, and beef demand•Issues in traceability with the supply chain of FBS is a crucial factor that affects market growth