Prefilled Syringes

This report covers the PFS market, both glass and plastics. The consolidated supply base, including the tubing segment is analyzed here

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Category Alerts


Stevanato collaborated with Recipharm to Develop Prefillable Syringes for Inhalers

March 27, 2023
alert level: Low

Meridian Medical Technologies announced that it would invest USD 100 million to build a new facility in the US

April 18, 2023
alert level: Low

Stevanato Group launches new COP and COC based plastic prefilled syringes

January 31, 2023
alert level: Medium

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Prefilled Syringes Industry Benchmarks

Savings Achieved

(in %)

The average annual savings achieved in Prefilled Syringes category is 8.00%

Payment Terms

(in days)

The industry average payment terms in Prefilled Syringes category for the current quarter is 70.0 days

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    Prefilled Syringes market report transcript

    Prefilled Syringes Global Market Demand

    • The global prefilled syringes market is forecasted to grow at 11–12 percent CAGR over 2024–2027, once the impact of COVID-19 moderates, driven by increasing demand from key downstream segments, such as biologics and insulin. Growing preference for PFS over other drug-delivery methods would also augment the market growth

    • The impact of COVID-19 has resulted in a significant demand hike in the market. As countries struggle with second and third waves of the pandemic, demand hike will continue until the end of 2023. Some of the vaccine manufacturers have chosen PFS as mode of packaging, which would further add to demand during this period

    • With a market share of about 35 percent, North America will continue to remain the largest regional market. The APAC is forecasted to witness the fastest demand growth with a CAGR of about 13–14 percent over the next five years, owing to the high occurrence of chronic lifestyle diseases and high growth for vaccines

    • Glass PFS hold a market share of about 70–75 percent but increasing technological advancements in polymer engineering and increasing demand for more complex device designs have resulted in growing penetration of plastic PFS devices. The demand for such plastic PFS is expected to grow at about 14–16 percent over the next five years, compared to about 9–10 percent for glass PFS

    Prefilled Syringes Regional Demand Overview

    • The global suppliers have engaged in acquisitions and partnerships to expand their product and technology capabilities and continue to invest into expansions in high growth markets of North America and APAC.

    Key Trends and Innovations : Prefilled Syringes

    Key Trend: Integrated Needle Stick Safety Device

    • Many markets in North America and Europe continue to introduce legislation to mandate the use of safety systems that prevent needlestick injuries that ensures end-user safety. As a result, market leaders have launched many innovative safety and shielding systems to incorporate such measures into the existing line of products and the new product developed by the suppliers.

    Key Trend:COP- COC based Plastic PFS

    • Issues, such as delamination and flaking in glass, have forced the industry to look for alternative materials in COC and COP plastics.

    • Compatibility issues with few complex formulations slowed penetration of such products, but innovations in these materials and launch of multi-layers systems that have the properties of both glass and plastics have driven penetration in the recent years.

    Key Trend: Customized Drug-Device Combinations

    • The advent of PFS and allied devices, such as auto-injectors, has given rise to a number of customized drug device combinations.

    • Pharma companies continue to switch to such systems, as they ensure dosage accuracy and prevent wastage. Also, devices, like Nemera’s Safelia systems, increase patient convenience by adopting minimal-invasive devices, like micro-needle injectors, spring-based auto injectors.

    Global Market Overview: PFS

    • PFS demand is expected to grow between 11 and 12 percent in the next five years, owing to the growing rate of chronic and lifestyle disease globally, growing legislature toward safety systems and large number of biologic drugs using PFS format.

    • PFS is the fastest growing segment within parenteral packaging, owing to the growing market for drug-device combinations, increasing need for safety, accuracy in dosage, and to reduce wastage

    • The pandemic has resulted in a shortage of vial-syringe packaging formats, owing to growing demand from vaccine manufacturing, and has also boosted the self-administration trend, owing to safety issues in visiting health care providers

    • Growth of PFS demand has also been aided by growing prevalence of chronic and lifestyle diseases. Diabetes accounted for about 30–35 percent of the overall PFS demand in 2020 and demand from diabetes segment is forecasted to grow at 13–15 percent over the next five years, making it the fastest growing of major segments

    • The pharma industry is also witnessing growing market share of biologics and biosimilars that use PFS as the preferred format of packaging

    • Increasing legislature toward better safety systems to prevent needlestick injuries are another key reasons driving adoption of PFS systems over conventional syringes. Growing crowds in hospitals have prompted higher occurrences of needlestick injuries, driving demand for needle-free systems and safety systems

    PFS: Downstream Demand

    • The vaccine market has increased by about 100–150 percent over 2020–2022, owing to COVID-19 vaccine efforts, and while demand has slowed, the increased demand would continue until 2023, while long-term demand would be driven by other vaccines and growing biopharma drugs.

    Key Downstream Demand Segments


    • Market share of biological drugs continue to increase Y-o-Y, owing to the number of biosimilars being launched in the market

    • In developing markets, such as APAC and LATAM, many new specialty biopharma startups have emerged that have launched new biosimilars depending on CMOs for manufacturing


    • The impact of pandemic and the global push for herd immunity will drive the demand for vaccine in the short term, while long-term demand growth will stem from other key vaccines, such as malaria and flu vaccine

    • Rising investments by emerging markets into healthcare infrastructure will continue to aid growth in vaccines demand


    • Growing prevalence of diabetes in the North American and Asian markets remains the key driver for insulin demand

    • Increasing competition in the market has resulted in cost competition, which has reduced growth forecast

    • Trend of self-administration for long-term care, along with growing technologies in drug delivery devices, has fostered growth in the market

    Downstream Demand Outlook

    Growing geriatric population

    • The World Bank estimates that the population aged over 60 would double from around 11–22 percent in 2050, especially in the emerging economies of APAC.

    Prevalence of chronic diseases

    • Increase in the prevalence of chronic diseases, such as cancer, diabetes, arthritis, and chronic intestinal diseases, will also play a role in ramping up the demand for parenteral packaging.

    Increasing government spending

    • Favorable government policies, combined with the rising adoption of injection-based treatment, will also continue to influence the market positively.

    Regional Market Overview of PFS

    • In the next 2–5 years, the market for traditional disposable syringe will be gradually replaced with safety PFS with advanced retractable features, owing to stringent regulations on needlestick injury prevention in the western market.

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