08 October, 2019
RALEIGH, North Carolina, October 8, 2019 - The global in-vitro toxicology testing market is currently estimated to be worth $4.6 billion and is expected to reach a value of $5.1 billion by 2020, according to Beroe Inc., a procurement intelligence firm. In-vitro toxicology accounts for approximately 30 percent of the overall toxicology testing market, with the remainder consists of in-vivo testing.
North America accounts for the largest share of over 40 percent revenue in the in-vitro toxicology market, followed by Europe with a 30 percent market share. The pricing model adoption rate for in-vitro services varies with the geographies, due to the variation in engagement terms, as well as the type and duration of the project outsourced. In developed markets, the FFS pricing model has a higher adoption rate while in emerging markets the FTE pricing model is more commonly adopted.
Beroe, which is based in North Carolina, further stated that procurement experts can access this report on its recently launched market intelligence platform Beroe LiVE: live.beroeinc.com
Opposition to animal testing in drug development, increase in global illicit drug abusers and increasing R&D to detect toxicity at early stages are factors that are driving the growth of the market. Other factors include the development of new technologies in analytical laboratories and the enhanced efficiency of in-vitro toxicology testing in cancer diagnosis. The predictive ability of the tests, stringent regulatory framework, and the inability of in-vitro models to detect certain anomalies are the major challenges faced by the market.
The emergence of new approaches of 3D cell culture can boost the market as 3D cell culture represents the next generation of in-vitro toxicology testing, especially in liver research. Organ-on-chip or tissue-on-chip is an in-vitro means used to access the safety and efficacy of drugs and therapeutics is also gaining in popularity, with recent experiments showing that organ-on-chip could lead to personalized treatments.
The research methodology adopted for the report included:
Around 99 percent of in-vitro toxicology testing usage is seen in the three main areas, namely ADME, safety pharmacology, and genotoxicity. However, there is concern about the global capacity for performing complex Genotoxicity studies, such as the Extended One-generation Reproductive Toxicity Study (EOGRTS) and higher-tier Ecotoxicity testing, as there are a limited number of CROs capable of conducting them.
The report also includes:
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