11 June, 2020
RALEIGH, North Carolina, Jun 11, 2020 - The COVID 19 pandemic has had a significant impact on industries and supply chains across the world; spurring some while constraining others. Currently, there are 1621 clinical trials related to COVID 19, whereas non-COVID trials have slowed down, according to Beroe Inc, a procurement intelligence firm.
Top Pharma companies to support the pandemic are working on vaccines, devices, scanning repurposing, RNA based treatments, cell-based therapies, antivirals, and antibodies. Major Pharma companies have changed their R&D plans through delays in site activation and delays in patient recruitment, to focus on COVID 19.
At a regional level, Europe currently has the maximum number of clinical trials underway for COVID 19, with a total of 628 trials, followed by North America with 383, Asia with 171, the Middle East with 83, Africa with 56, LATAM with 48, and Australia with 10. Oxford has engaged with 7 manufacturers across Europe, India and China to mass produce its Adenovirus based vaccine ChAdOx1 nCoV-19, a few million of which are expected to become available by September 2020.
Beroe, which is based in North Carolina, further stated that procurement experts can access this report on market intelligence platform Beroe LiVE: live.beroeinc.com
Vaccines developing under the genetic engineering model have gained traction due to the pandemic scenario, where the genome of the virus is captured and a blueprint is made of RNA or DNA or Adenovirus which hold genetic instructions. This model of vaccine has existed for more than 3 decades, but only in labs. This process doesn’t consume time and can be produced at a faster pace. Companies would prefer to work with remote healthcare monitoring and tele-health devices, thereby pharma could cut down cost on unnecessary COVID visits to sites and hospitals
There has been an improved adherence of EHR`and other databases, as patients and HCPs prefer remote and electronic trials. This indirectly helps pharma access to authentic patient data Operation of the labs are hindered which causes a significant delay in trial and testing timelines. Sample transport and investigator support is suffering a setback. However virtual tools and technology support enables a better situation to pharma companies. Trial results are impacted thus increasing clinical trial failures.
The research methodology adopted for the report included:
Top pharma companies are working on several vaccines for COVID 19 that are in various phases of clinical trials. In phase III currently there are Gilead, working on Treatment targeting Remdesivir, Abbvie, working on Treatment targeting Lopinavir/itonavir combination, Roche (Chugai), working on Treatment targeting Actemra®, and Novartis, working on Treatment targeting Jakavi® (ruxolitinib). INOVIO is in Phase II of MERS Vaccine (related Coronavirus) using DNA, helping design a DNA vaccine for COVID-19 within a few hours from the release of the virus’s genetic sequence by Chinese scientists.
The report also includes:
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SOURCE: Beroe Inc.
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