18 June, 2020
RALEIGH, North Carolina, Jun 18, 2020 - The coronavirus pandemic has had a major impact on industries worldwide, including clinical research. Except for on-going trials, those trials that had started recruiting or were about to start have been halted. Pre-clinical testing for new drugs might slow down due to lockdown in all major countries except drugs or vaccines for COVID-19, according to Beroe Inc, a procurement intelligence firm.
A majority of top pharma companies are engaged in clinical research on vaccines, followed by antibodies, antivirals, cell-based therapies, devices and RNA based treatments.
There has been an increase in regional approaches in clinical research, as a result of COVID-19, as sponsors in the near and long term would not prefer in-sourcing chemists from China or other international countries given the pandemic conditions. This could result in development of strategic partnerships with regional companies. Majority of sponsor companies maintain partnerships with Wuxiapptec, Medicilon and a number of other preclinical companies in the APAC region. The COVID-19 pandemic could hugely impact the logistics of samples, import-export etc. slowing down the process of discovery.
Beroe, which is based in North Carolina, further stated that procurement experts can access this report on market intelligence platform Beroe LiVE: live.beroeinc.com
There is a high demand of service providers who provide in vivo toxicology studies as data on in-vitro/in-vivo activity of the candidate helps therapeutics against COVID19, and in considerations regarding dosage, route of and time for administration, as well as safety and efficacy data in humans. There is also an increase in the need for biomarkers for COVID research, as it is essential to understand the disease nature where a lot of research companies are involved in understanding the pandemic uplifting the research market.
The coronavirus pandemics has led to a significant increase in investments in artificial intelligence and other new technologies as the adoption of AI would rise. Pharma would aim to speed up the discovery process by identifying potential therapeutic targets and staying on top of the competition. Based on impact on all Preclinical testing, sponsors would in the near term invest heavily on technology platforms for target identification, high throughput, real-world evidence, etc. on therapeutic targets.
The research methodology adopted for the report included:
Several of the top pharma companies around the world are in preclinical stages of researching treatments and vaccines. Sanofi is researching treatment and vaccine targeting Plaquenil, Novavax is researching vaccine targeting NVX-CoV2373, and GSK and Vir Biotechnology are researching vaccines targeting VIR-7831 and VIR-7832. Meanwhile, Sanofi and Translate Bio are researching vaccine targeting mRNA for COVID-19, Takeda Treatment is researching treatments for Anti-SARS-CoV-2 polyclonal hyperimmune globulin (H-IG), and J&J is researching vaccines targeting modified adenovirus.
The report also includes:
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